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Mouse Monoclonal anti-Synaptotagmin-3 Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0905
ID Mouse Monoclonal anti-Synaptotagmin-3 Antibody
Antigen Description Synaptotagmin-3 (SYT3)  is a member of the synaptotagmin family, which consists of 13  membrane trafficking proteins that contain a N-terminal transmembrane region, and two cytoplasmic C2 domains. Synaptotagmin-3 is mainly localized at the presynaptic terminals in the central nervous system, where it functions as a Ca2+ sensor and plays an important role in exocytosis of secretory vesicles and neurotransmitter release. It has been shown that Ca2+ influx triggers the interaction between the C2-domains of SYT3 and the phospholipid membranes.
Size 100ug
Immunogen Fusion protein corresponding to amino acids 442-533 (cytoplasmic C2B domain) of mouse Synaptotagmin-3
Clone #N278/19
Antibody Isotype Mouse IgG1
Host Species Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application WB
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.