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Armenian Hamster Monoclonal anti-Mouse/Rat CD61 Antibody


Item#:
xAP-0853
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0853
ID Armenian Hamster Monoclonal anti-Mouse/Rat CD61 Antibody
Antigen Description CD61 is a 110 kD integrin ß chain also known as ß3 integrin or gpIIIa. It associates with the integrin av chain (CD51) to form the vitronectin receptor. In addition, CD61 can associate with the integrin aIIb chain (CD41) to form the gpIIb/IIIa complex. CD61 is expressed on platelets, megakaryocytes, endothelium, smooth muscle, a subset of B cells, myeloid cells, osteoclasts, and mast cells. CD61, in conjunction with CD41 or CD51, mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is mediated by the binding of av/ß3 integrin or vitronectin receptor to CD31 (PECAM-1).
Size 100ug
Immunogen Vitronectin receptor protein from the mouse T-cell hybridoma 2B4.
Clone #2C9.G2 (HMß3-1)
Antibody Isotype Armenian Hamster IgG
Species Reactivity Armenian Hamster
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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