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Rat Monoclonal anti-Mouse TLR4 (CD284)/MD2 Complex Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0831
ID Rat Monoclonal anti-Mouse TLR4 (CD284)/MD2 Complex Antibody
Antigen Description Toll-like receptors are highly conserved from Drosophila to humans and share structural and functional similarities. They are type I transmembrane signaling receptors which activate the innate immune system in response to pathogen invasion. So far, at least 13 TLR members have been identified. The secretory protein, MD2, associates with cell-surface bound TLR4 (CD284) on monocytes, B cells and T cells. TLR4 has been recognized as critical for host recognition of bacterial LPS in conjunction with MD2.
Size 100ug
Immunogen Ba/F3 cell line transfected with mouse TLR4 /MD2 complex
Clone #MTS510
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-P WBICFC IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.