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Armenian Hamster Monoclonal anti-Mouse TCR ¿/d Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0823
ID Armenian Hamster Monoclonal anti-Mouse TCR ¿/d Antibody
Antigen Description T cell receptor (TCR) is a heterodimer consisting of an a and a ß chain (TCR a/ß) or a ¿ and a d chain (TCR ¿/d). TCR ¿/d belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR ¿/d associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most ¿/d T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR ¿/d have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that ¿/d T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-¿/d-bearing T cells in vitro, and to deplete peripheral TCR-¿/d-bearing T cells in vivo.
Size 100ug
Immunogen Recombinant mouse TCR ¿/d
Clone #UC7-13D5
Antibody Isotype Armenian Hamster IgG
Species Reactivity Armenian Hamster
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP Stim Depletion
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.