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Rat Monoclonal anti-Mouse TCR Vß8.1, 8.2 Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0816
ID Rat Monoclonal anti-Mouse TCR Vß8.1, 8.2 Antibody
Antigen Description The TCR Vß 8 family consists of three members, namely Vß8.1, 8.2 and 8.3. KJ16-133.18 reacts with Vß8.1, 8.2 only, but not Vß8.3. Most mouse strains have about 20% Vß 8+ T cells in the periphery.However, C57BR, C57L, SJL, SWR (Tcra haplotype) and RIII strains (Tcrc haplotype) do not express Vß8 due to a gene deletion at the Vß 8 family loci.Other strains expressing endogenous super-antigen, such as Mls-1a have significant reduced number of Vß 8.1 cells in the periphery.Exogenous superantigen, such as staphylococcal enterotoxin B, stimulates lymphocytes bearing Vß 8 and selectively eliminate those T cells in vivo.
Size 100ug
Immunogen TCR receptor from T cell hybridoma DO-11.10
Clone #KJ16-133.18
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.