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Rat Monoclonal anti-Mouse LPAM-1 (Integrin a4ß7) Antibody


Item#:
xAP-0779
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0779
ID Rat Monoclonal anti-Mouse LPAM-1 (Integrin a4ß7) Antibody
Antigen Description DATK32 antibody is specific for a combinatorial determinate of integrin a4ß7complex. Integrin a4ß7 is composed of a 150 kD (a4 or CD49d) and a 130 kD (ß7) heterodimer, also known as CD49d/ß7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin a4ß7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
Size 100ug
Immunogen TK1 cells
Clone #DATK32
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC Block IP IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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