Rat Monoclonal anti-Mouse IL-10 Antibody

Item#:

xAP-0756

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0756
ID	Rat Monoclonal anti-Mouse IL-10 Antibody
Antigen Description	IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-¿, TNF-ß, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-a synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.
Size	100ug
Immunogen	E. coli-expressed, recombinant mouse IL-10
Clone	#JES5-16E3
Antibody Isotype	Rat IgG2b
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	ELISA Capture CyTOF®IHC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.