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Mouse Monoclonal anti-Mouse I-Ak (Aak) Antibody


Item#:
xAP-0746
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0746
ID Mouse Monoclonal anti-Mouse I-Ak (Aak) Antibody
Antigen Description The 11-5.2 antibody reacts with the a chain of the I-Ak MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 11-5.2 antibody cross-reacts with cells from mice bearing the H-2r haplotype. Reactivity with other H-2 haplotypes (e.g., b, d, f, p, q, s) has not been observed. The 11-5.2 antibody has been reported to block antigen presentation and induce B cell differentiation.
Size 100ug
Immunogen CKB mouse splenocytes
Clone #11-5.2
Antibody Isotype Mouse (BALB/c) IgG2b, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-F IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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