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Rat Monoclonal anti-Mouse Folate Receptor ß (FR-ß) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0723
ID Rat Monoclonal anti-Mouse Folate Receptor ß (FR-ß) Antibody
Antigen Description Folate receptor beta (FR-ß) is a member of a family of folate binding receptors that have diverse structural identities but mediate transport of folates into cells. FR-ß is a GPI-anchored protein with high affinity for folic acid. It is postulated that this receptor function as folate scavengers when folate supply is low or rapid cell growth requires elevated uptake of folate for methylation reactions including DNA biosynthesis. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Size 100ug
Immunogen Mouse Folate receptor ß transfected cells
Clone #10/FR2
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.