Rat Monoclonal anti-Mouse Folate Receptor ß (FR-ß) Antibody

Item#:

xAP-0723

Size	Price	Quantity
100.0 ug	$420.00

Catalog Number	xAP-0723
ID	Rat Monoclonal anti-Mouse Folate Receptor ß (FR-ß) Antibody
Antigen Description	Folate receptor beta (FR-ß) is a member of a family of folate binding receptors that have diverse structural identities but mediate transport of folates into cells. FR-ß is a GPI-anchored protein with high affinity for folic acid. It is postulated that this receptor function as folate scavengers when folate supply is low or rapid cell growth requires elevated uptake of folate for methylation reactions including DNA biosynthesis. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
Size	100ug
Immunogen	Mouse Folate receptor ß transfected cells
Clone	#10/FR2
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.