Armenian Hamster Monoclonal anti-Mouse FceRIa Antibody

Item#:

xAP-0721

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0721
ID	Armenian Hamster Monoclonal anti-Mouse FceRIa Antibody
Antigen Description	FceRIa is a transmembrane protein belonging to the Ig superfamily. FceRIa forms a tetrameric complex with one ß and two ¿-subunits. The FceRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FceRIa, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FceRIa subunit.
Size	100ug
Immunogen	Recombinant mouse FceRIa
Clone	#MAR-1
Antibody Isotype	Armenian Hamster IgG
Host Species	Armenian Hamster
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.