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Armenian Hamster Monoclonal anti-Mouse CD79b (Igß) Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0692
ID Armenian Hamster Monoclonal anti-Mouse CD79b (Igß) Antibody
Antigen Description Mouse CD79b (Igß chain) is a 35-40kD transmembrane protein that forms a heterodimer with CD79a (30-35 kD, Ig a chain). The CD79b and CD79a hererodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79b participates in the signal transduction involved in development of B cells as well. It was reported that association between CD79b/CD79a with IgM is essential in inducing both the transition from progenitor to precursor B cells and subsequent allelic exclusion. Igß knockout mice had a complete block in B cell development at the immature CD43+B220+ stage. The HM79b-12 clone reacts with an extracellular epitope of CD79b or Igß.
Size 100ug
Immunogen Recombinant mouse CD79b (Igß)
Clone #HM79-12
Antibody Isotype Armenian Hamster IgG
Host Species Armenian Hamster
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.