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Rat Monoclonal anti-Mouse CD49e Antibody


Item#:
xAP-0670
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0670
ID Rat Monoclonal anti-Mouse CD49e Antibody
Antigen Description CD49e is a 135 kD protein, also known as a5 integrin or VLA-5 a chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin ß1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells.
Size 100ug
Immunogen (C57BL/6 x A/J)F1 mouse mast cell line
Clone #5H10-27(MFR5)
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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