Rat Monoclonal anti-Mouse CD49e Antibody

Item#:

xAP-0670

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0670
ID	Rat Monoclonal anti-Mouse CD49e Antibody
Antigen Description	CD49e is a 135 kD protein, also known as a5 integrin or VLA-5 a chain. It is a member of the integrin family, expressed on thymocytes, splenic B cells, activated T cells, and mast cells. CD49e associates with CD29 (integrin ß1 chain) to form the fibronectin receptor (VLA-5). CD49e plays a critical role in both adhesion and T cell costimulation. The primary ligand for CD49e/CD29 (VLA-5) is fibronectin. The 5H10-27(MFR5) antibody has been shown to block CD49e mediated interactions and promote the in vitro stimulation of CD8+ T cells.
Size	100ug
Immunogen	(C57BL/6 x A/J)F1 mouse mast cell line
Clone	#5H10-27(MFR5)
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.