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Rat Monoclonal anti-Mouse CD49d Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0669
ID Rat Monoclonal anti-Mouse CD49d Antibody
Antigen Description CD49d is a 150 kD glycoprotein, also known as a4 integrin or VLA-4 a chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two ß chains, ß1 (CD29) or ß7, to form the VLA-4 (integrin a4ß1) or LPAM-1 (integrin a4ß7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. The 9C10(MFR4.B) antibody, in combination with the R1-2 monoclonal antibody, completely blocks VCAM-1 binding to VLA-4.
Size 100ug
Immunogen (C57BL/6 x A/J)F1 mouse fetal liver mas
Clone #9C10 (MFR4.B)
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC Block IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.