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Rat Monoclonal anti-Mouse CD49b (pan-NK cells) Antibody


Item#:
xAP-0667
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0667
ID Rat Monoclonal anti-Mouse CD49b (pan-NK cells) Antibody
Antigen Description DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin a chain also known as a2 integrin, VLA-2 a chain, and integrin a2 chain. CD49b non-covalently associates with CD29 (ß1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Size 100ug
Immunogen IL-2-propagated NK1.1+ cells from C57BL/6 mice
Clone #DX5
Antibody Isotype Rat IgM, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-P IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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