Rat Monoclonal anti-Mouse CD49b (pan-NK cells) Antibody

Item#:

xAP-0667

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0667
ID	Rat Monoclonal anti-Mouse CD49b (pan-NK cells) Antibody
Antigen Description	DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin a chain also known as a2 integrin, VLA-2 a chain, and integrin a2 chain. CD49b non-covalently associates with CD29 (ß1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Size	100ug
Immunogen	IL-2-propagated NK1.1+ cells from C57BL/6 mice
Clone	#DX5
Antibody Isotype	Rat IgM
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-P IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.