Rat Monoclonal anti-Mouse CD47 Antibody

Item#:

xAP-0664

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0664
ID	Rat Monoclonal anti-Mouse CD47 Antibody
Antigen Description	CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPa, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Size	100ug
Immunogen	Recombinant mouse CD47
Clone	#miap301
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.