Rat Monoclonal anti-Mouse CD45RB Antibody

Item#:

xAP-0662

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0662
ID	Rat Monoclonal anti-Mouse CD45RB Antibody
Antigen Description	CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naÃ¯ve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naÃ¯ve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
Size	100ug
Immunogen	Cloned mouse Th2 cell lines
Clone	#C363-16A
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-P IHC-F IP
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.