Rat Monoclonal anti-Mouse CD366 (Tim-3) Antibody

Item#:

xAP-0635

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0635
ID	Rat Monoclonal anti-Mouse CD366 (Tim-3) Antibody
Antigen Description	CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b+ macrophages. Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Size	100ug
Immunogen	Recombinant mouse CD366 (Tim-3)
Clone	#RMT3-23
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC Block IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.