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Rat Monoclonal anti-Mouse CD273 (B7-DC, PD-L2) Antibody


Item#:
xAP-0601
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0601
ID Rat Monoclonal anti-Mouse CD273 (B7-DC, PD-L2) Antibody
Antigen Description B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. The TY25 antibody has been reported to be useful for blocking PD-1 mediated interactions.
Size 100ug
Immunogen Mouse B7-DC transfected cell line
Clone #TY25
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-F IP WB
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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