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Rat Monoclonal anti-Mouse CD253 (TRAIL) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0595
ID Rat Monoclonal anti-Mouse CD253 (TRAIL) Antibody
Antigen Description CD253 is a 40 kD TNF superfamily member known as TRAIL, Apo-2 ligand, and Apo-2L. TRAIL is expressed on a variety of cells, including IL-2 and IL-15 activated NK cells and activated T cells. However, it is undetectable on resting T and B cells. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. The N2B2 antibody has been reported to be useful for flow cytometric staining and blocking NK cell cytotoxicity in vitro.
Size 100ug
Immunogen Mouse TRAIL-transfected 2PK-3 cells
Clone #N2B2
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC Block
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.