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Rat Monoclonal anti-Mouse CD215 (IL-15Ra) Antibody


Item#:
xAP-0580
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0580
ID Rat Monoclonal anti-Mouse CD215 (IL-15Ra) Antibody
Antigen Description IL-15 receptor a (IL-15Ra) is a cytokine receptor with the structural homology to IL-2Ra (CD25). Both a receptors contain a group of ß sandwich protein called sushi domains. Similar to IL-2Ra, IL-15Ra is able to form a heterotrimer with their ß chain (CD122) and common ¿ chain (¿c, CD132). But unlike IL-2Ra subunit, IL-15Ra itself binds to IL-15 with equivalent high affinity compared with the heterotrimeric complex. IL-15Ra is expressed as soluble or transmembrane forms by variety cells, such as activated monocytes, dendritic cells, CD8+ memory T cells, NK or NKT cells. IL-15Ra by itself forms stable complexes with IL-15 on cell surface and presents IL-15 in trans to neighboring cells. IL-15, like IL-2, is a pleiotropic four-helix bundle cytokine and plays a key role in promoting T and B cell survival and proliferation, preferentially in memory CD8+ T cell proliferation, and NK/NKT cell development.
Size 100ug
Immunogen Mouse CD215 recombinant protein (33-205 a.a.)
Clone #6B4C88
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC 
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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