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Rat Monoclonal anti-Mouse CD140b Antibody


Item#:
xAP-0535
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0535
ID Rat Monoclonal anti-Mouse CD140b Antibody
Antigen Description Platelet-derived growth factor receptor-ß (PDGFR-ß), CD140b, is one of two receptors for platelet-derived growth factors (PDGFs) and binds to all isoforms of PDGFs. PDGFRß is a receptor tyrosine kinase that forms homodimers or heterodimers on the surface upon ligand binding and phosphorylates substrates. PDGFRs consist of either homodimers of a/a, ß/ß, or heterodimers of a/ß. PDGF receptors, a and ß, are single glycoproteins with intracellular tyrosine kinase domain. Their ligand, PDGF, is a mitogen for connective tissue and glial cells. CD140b is expressed on embryonic tissues and mesenchymal-derived cells adult mice. PDGF plays a role in wound healing and acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes, and neutrophils.
Size 100ug
Immunogen Mouse PDGFR-ß-hIgG1 recombinant fusion protein
Clone #APB5
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC WB Block
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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