Rat Monoclonal anti-Mouse CD126 (IL-6Ra) Antibody

Item#:

xAP-0524

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0524
ID	Rat Monoclonal anti-Mouse CD126 (IL-6Ra) Antibody
Antigen Description	CD126 (IL-6Ra) is an 80kD member of the immunoglobulin superfamily that is expressed on activated T and B cells, monocytes, hepatocytes, and plasma cells. High affinity IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor ß chain (CD130 or gp130). CD126 binds IL-6 with low affinity, but does not signal. The ß chain (gp130, CD130) does not bind IL-6 by itself, but associates with the a-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation.
Size	100ug
Immunogen	Mouse IL-6R recombinant protein, 1-357 a.a.
Clone	#W18166A
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC Block
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.