Rat Monoclonal anti-Mouse CD125 (IL-5Ra) Antibody

Item#:

xAP-0523

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0523
ID	Rat Monoclonal anti-Mouse CD125 (IL-5Ra) Antibody
Antigen Description	CD125 is a 60KDa type I transmembrane protein. It is the ligand-specific a subunit of the heterodimeric interleukin 5 (IL-5) receptor. The signal-transducing ß subunit of this receptor does not bind to any cytokines and is shared by the receptors for IL-3 and CSF2/GM-CSF. IL-5 is mainly produced by Th2 cells and elevated IL-5 levels are associated with allergic disorders. CD125 has also been found to interact with syndecan binding protein (SDCBP or syntenin), leading to the activation of the transcription factor SOX4. The mouse CD125 is expressed on eosinophils, basophils, and B cells.
Size	100ug
Immunogen	Murine IL-5Ralpha-hFcgamma1 fusion protein
Clone	#DIH37
Antibody Isotype	Rat IgG2a
Host Species	Rat
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.