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Rat Monoclonal anti-Mouse CD125 (IL-5Ra) Antibody


Item#:
xAP-0523
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0523
ID Rat Monoclonal anti-Mouse CD125 (IL-5Ra) Antibody
Antigen Description CD125 is a 60KDa type I transmembrane protein.  It is the ligand-specific a subunit of the heterodimeric interleukin 5 (IL-5) receptor. The signal-transducing ß subunit of this receptor does not bind to any cytokines and is shared by the receptors for IL-3 and CSF2/GM-CSF.  IL-5 is mainly produced by Th2 cells and elevated IL-5 levels are associated with allergic disorders.  CD125 has also been found to interact with syndecan binding protein (SDCBP or syntenin), leading to the activation of the transcription factor SOX4.  The mouse CD125 is expressed on eosinophils, basophils, and B cells.
Size 100ug
Immunogen Murine IL-5Ralpha-hFcgamma1 fusion protein
Clone #DIH37
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC 
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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