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Rat Monoclonal anti-Mouse CD122 (IL-2Rß) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0521
ID Rat Monoclonal anti-Mouse CD122 (IL-2Rß) Antibody
Antigen Description CD122 is a 70-75 kD IL-2 receptor ß chain also known as IL-2Rß, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rß chain can combine with either the common ¿ subunit (¿c, CD132) alone or with the ¿c subunit and the IL-2Ra subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Size 100ug
Immunogen Rat myeloma YB2/0 transfected with truncated mouse Il-2Rß cDNA
Clone #5H4
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.