Armenian Hamster Monoclonal anti-Mouse CD121a (IL-1 R, Type I/p80) Antibody

Item#:

xAP-0520

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0520
ID	Armenian Hamster Monoclonal anti-Mouse CD121a (IL-1 R, Type I/p80) Antibody
Antigen Description	CD121a is an 80 kD IL-1 receptor type I. It is a transmembrane glycoprotein and a member of the immunoglobulin superfamily expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. CD121a binds the mature forms of IL-1a, IL-1ß, and IL-1Ra proteins. High affinity binding and signaling by the type I IL-1 receptor requires CD121a and the accessory protein, IL-1R AcP, which does not bind IL-1 alone, but forms a dimer capable of binding IL-1.
Size	100ug
Immunogen	Extracellular domain of mouse IL-1R1
Clone	#JAMA-147
Antibody Isotype	Armenian Hamster IgG
Host Species	Armenian Hamster
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IP
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.