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Armenian Hamster Monoclonal anti-Mouse CD119 (IFN-¿ R a chain) Antibody


Item#:
xAP-0512
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0512
ID Armenian Hamster Monoclonal anti-Mouse CD119 (IFN-¿ R a chain) Antibody
Antigen Description CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-¿Ra chain. It is a class II cytokine receptor family member that serves as a IFN-¿-binding chain associated with the IFN-¿ ß chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-¿ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-¿ initiates and regulates a variety of immune responses.
Size 100ug
Immunogen Soluble recombinant mouse IFN-¿R a chain protein
Clone #2E2
Antibody Isotype Armenian Hamster IgG
Species Reactivity Armenian Hamster
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP WB
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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