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Rat Monoclonal anti-Mouse CD107b (Mac-3) Antibody


Item#:
xAP-0504
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0504
ID Rat Monoclonal anti-Mouse CD107b (Mac-3) Antibody
Antigen Description Mac-3 is a 110 kD type I membrane glycoprotein, also known as CD107b and LAMP-2. It is expressed on lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. In the bone marrow, few cells display Mac-3 antigen on the surface, but a large proportion express Mac-3 in the cytoplasm. CD107b has been identified as a ligand for galaptin, an S-type lectin present in the extracellular matrix. Mac-3/CD107b is upregulated in some tumors and increased expression has been correlated with enhanced metastatic potential.
Size 100ug
Immunogen Membrane glycoproteins from C57BL/6 mouse peritoneal exudate cells
Clone #M3/84
Antibody Isotype Rat IgG1, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP ICC IHC-P IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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