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Rat Monoclonal anti-Mouse CD106 Antibody


Item#:
xAP-0502
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0502
ID Rat Monoclonal anti-Mouse CD106 Antibody
Antigen Description CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (a4/ß1 integrin) and LPAM-1 (a4/ß7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.
Size 100ug
Immunogen Mouse preadipose cell line PA6
Clone #429 (MVCAM.A)
Antibody Isotype Rat IgG2a, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-F IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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