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Armenian Hamster Monoclonal anti-Mouse CD103 Antibody


Item#:
xAP-0498
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0498
ID Armenian Hamster Monoclonal anti-Mouse CD103 Antibody
Antigen Description CD103 is a type I transmembrane glycoprotein known as aE integrin or Integrin aIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-ß stimulation. In association with integrin ß7, CD103 is expressed as aE/ß7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Size 100ug
Immunogen Mouse intestinal intraepithelial lymphocytes
Clone #2E7
Antibody Isotype Armenian Hamster IgG
Species Reactivity Armenian Hamster
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-F IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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