Armenian Hamster Monoclonal anti-Mouse CD103 Antibody

Item#:

xAP-0498

Size	Price	Quantity
100.0 ug	$400.00

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Product Overview

Catalog Number	xAP-0498
ID	Armenian Hamster Monoclonal anti-Mouse CD103 Antibody
Antigen Description	CD103 is a type I transmembrane glycoprotein known as aE integrin or Integrin aIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-ß stimulation. In association with integrin ß7, CD103 is expressed as aE/ß7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Size	100ug
Immunogen	Mouse intestinal intraepithelial lymphocytes
Clone	#2E7
Antibody Isotype	Armenian Hamster IgG
Host Species	Armenian Hamster
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IHC-F IP
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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