Mouse Monoclonal anti-Human/Rat CD51 (Integrin avß5) Antibody

Item#:

xAP-0483

Size	Price	Quantity
100.0 ug	$400.00

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Product Overview

Catalog Number	xAP-0483
ID	Mouse Monoclonal anti-Human/Rat CD51 (Integrin avß5) Antibody
Antigen Description	CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor a chain, or integrin aV. It forms heterodimer with integrin ß1 (CD29), ß3 (CD61), ß5, ß6, or ß8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its ß chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling and mediates bone absorption and angiogenesis.
Size	100ug
Immunogen	The P1F6 monoclonal antibody was generated against human small cell lung carcinoma cells (UCLA P3).
Clone	#P1F6
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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