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Rat Monoclonal anti-Human/Mouse Integrin ß7 Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0477
ID Rat Monoclonal anti-Human/Mouse Integrin ß7 Antibody
Antigen Description Integrin ß7 is a 130 kD glycoprotein also known as integin ßp. It is a member of the Ig superfamily. In association with integrin a4 or aE chain, ß7 forms a4/ß7 or aE/ß7 heterodimer. a4/ß7 (CD49d/ß7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. aE/ß7 (CD103/ß7,aIEL/ß7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/ß7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
Size 100ug
Immunogen TK1 cells
Clone #FIB504
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.