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Rat Monoclonal anti-Human/Mouse Cutaneous Lymphocyte Antigen (CLA) Antibody


Item#:
xAP-0475
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0475
ID Rat Monoclonal anti-Human/Mouse Cutaneous Lymphocyte Antigen (CLA) Antibody
Antigen Description Cutaneous lymphocyte antigen (CLA) is a 140 kD homodimer protein recognized by a unique mAb, HECA-452. It is expressed on T cells in skin, subsets of peripheral blood memory T cells, NK cells, memory B cells and dendritic cells as well as on monocytes, granulocytes, and activated endothelial cells. CLA is a carbohydrate epitope of sialic acid and fucose-modified P-selectin glycoprotein ligand-1 (PSGL-1), a surface glycoprotein expressed on the majority of peripheral blood leukocytes. CLA is a ligand for E-selectin, P-selectin, and L-selectin. It plays a role in memory lymphocyte homing, tethering, and rolling.
Size 100ug
Immunogen Recombinant human/mouse Cutaneous Lymphocyte Antigen (CLA)
Clone #HECA-452
Antibody Isotype Rat IgM, ¿
Species Reactivity Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-PIHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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