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Mouse Monoclonal anti-Human/Mouse CD3e (activation epitope) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0473
ID Mouse Monoclonal anti-Human/Mouse CD3e (activation epitope) Antibody
Antigen Description The CD3e chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex.  This conformational change leads to exposure of the proline rich sequence in CD3e and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 a/ß or ¿/d and ¿ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency.
Size 100ug
Immunogen Purified denatured CD3 proteins from human thymus
Clone #APA1/1
Antibody Isotype Mouse IgG1
Host Species Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application ICFC WB IHC-Pin vivo cell tracking
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.