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Mouse Monoclonal anti-Human TCR Va24-Ja18 (iNKT cell) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0460
ID Mouse Monoclonal anti-Human TCR Va24-Ja18 (iNKT cell) Antibody
Antigen Description Encoded by the TCR Va24-Ja18 germline configuration, Va24-JaQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Va24-JaQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
Size 100ug
Immunogen Recombinant human TCR Va24-Ja18 (iNKT cell)
Clone #6B11
Antibody Isotype Mouse IgG1
Host Species Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.