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Mouse Monoclonal anti-Human CD51 Antibody


Item#:
xAP-0297
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0297
ID Mouse Monoclonal anti-Human CD51 Antibody
Antigen Description CD51 is a type I integral membrane glycoprotein, known as vitronectin receptor a chain, or integrin aV. It forms heterodimer with integrin ß1 (CD29), ß3 (CD61), ß5, ß6, or ß8. CD51 contains two disulfide-linked subunits of 125 kD and 24 kD, and is expressed on endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its ß chains, CD51 binds vitronectin, von Willebrand factor, fibronectin, thrombospondin, osteopontin, fibrinogen, and laminin. CD51, as an adhesion molecule, plays important roles in leukocytes homing and rolling, mediates bone absorption and angiogenesis.
Size 100ug
Immunogen Melonama cells
Clone #NKI-M9
Antibody Isotype Mouse IgG2a, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC ICCELISA Block IP
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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