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Mouse Monoclonal anti-Human CD49c (integrin a3) Antibody


Item#:
xAP-0291
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0291
ID Mouse Monoclonal anti-Human CD49c (integrin a3) Antibody
Antigen Description CD49c is a 150 kD a integrin chain known as a3 integrin or VLA-3 a chain. It is a type I transmembrane glycoprotein which is proteolytically cleaved into two disulfide linked fragments of 125 kD and 30 kD. CD49c forms a heterodimer with integrin ß1 (a3ß1, CD49c/CD29, VLA-3) and is expressed by many types of adhesion cells, such as endothelial cells, epithelial cells, and dermal fibroblasts. Weak expression has been reported on leukocytes. VLA-3 plays a role in cell-cell and cell-matrix adhesion through binding Kalinin, collagen, laminin-1, laminin-5, entactin, and fibronectin.
Size 100ug
Immunogen Human squamous cell carcinoma cell line SCC-9
Clone #ASC-1
Antibody Isotype Mouse IgG1, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP WB IHC-F
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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