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Mouse Monoclonal anti-Human CD49b Antibody


Item#:
xAP-0290
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0290
ID Mouse Monoclonal anti-Human CD49b Antibody
Antigen Description CD49b is a 170 kD transmembrane protein, also known as a2 integrin, VLA-2 a chain, Integrin a2 and GPIa. It associates with CD29 (ß1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
Size 100ug
Immunogen HT1080 cells
Clone #P1E6-C5
Antibody Isotype Mouse IgG1, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IP ELISA
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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