Mouse Monoclonal anti-Human CD34 Antibody

Item#:

xAP-0245

Size	Price	Quantity
100.0 ug	$400.00

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Product Overview

Catalog Number	xAP-0245
ID	Mouse Monoclonal anti-Human CD34 Antibody
Antigen Description	CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Since it is selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands. About 40% of acute myeloid leukemias and 65% of pre-B acute lymphoblastic leukemias express CD34, whereas only 1-5% of acute T-lymphoid leukemias are CD34 positive.
Size	100ug
Immunogen	Human CD34-transfected cells
Clone	#S20016E
Antibody Isotype	Mouse IgG2a
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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