Home Page > ANTIBODY > MONOCLONAL ANTIBODY > Common Antibody >  Mouse Monoclonal anti-Human CD274 (B7-H1, PD-L1) Antibody

Mouse Monoclonal anti-Human CD274 (B7-H1, PD-L1) Antibody


Item#:
xAP-0208
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0208
ID Mouse Monoclonal anti-Human CD274 (B7-H1, PD-L1) Antibody
Antigen Description CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-¿ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Size 100ug
Immunogen Full length human PD-L1
Clone #29E.2A3
Antibody Isotype Mouse IgG2b, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC-PBlock
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

ANGIO-PROTEOMIE, ALL RIGHTS RESERVED