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Mouse Monoclonal anti-Human CD255 (TWEAK) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0200
ID Mouse Monoclonal anti-Human CD255 (TWEAK) Antibody
Antigen Description TNF-like weak inducer of apoptosis (TWEAK) is a type II transmembrane TNF superfamily member with strong homology to TNF in its extracellular portion, though less potent in inducing apoptosis. It has been clustered as CD255. TWEAK transcript is expressed broadly in many adult and fetal tissues; however, the staining of human peripheral blood mononuclear cells with TWEAK-specific antibodies shows a more restricted pattern. TWEAK is expressed as membrane-bound and secreted forms. Interaction of TWEAK with its receptors (DR3, Fn14) promotes secretion of IL-8, activation of NF-¿B, proliferation of endothelial cells, and apoptosis in a number of human cell lines.
Size 100ug
Immunogen hTWEAK/2PK-3 transfectant cells
Clone #CARL-1
Antibody Isotype Mouse IgG3, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.