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Mouse Monoclonal anti-Human CD221 (IGF-1R) Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0181
ID Mouse Monoclonal anti-Human CD221 (IGF-1R) Antibody
Antigen Description CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies reveal its function of recruiting immune cells during tissue repair.
Size 100ug
Immunogen IGF-1 receptor purified from human placentas
Clone #1H7/CD221
Antibody Isotype Mouse IgG1
Host Species Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC IHC IP WB
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.