Mouse Monoclonal anti-Human CD169 (Sialoadhesin, Siglec-1) Antibody

Item#:

xAP-0139

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0139
ID	Mouse Monoclonal anti-Human CD169 (Sialoadhesin, Siglec-1) Antibody
Antigen Description	CD169, also known as Siglec-1 and Sialoadhesin (Sn), is a 210 kD type I single membrane-spanning glycoprotein. It is the largest member of the Siglec family, consisting of 1709 amino acids and belonging to the immunoglobulin superfamily. CD169 is expressed by macrophages and dendritic cells. By its affinity to a2,3-linked sialic acid, it is involved in macrophage binding to different cell types such as granulocytes, monocytes, NK, B and T cells. Several CD169 counter receptors, such as CD227 on human breast cancer cells, CD43 on T cells and CD206 on macrophages, have been reported.
Size	100ug
Immunogen	Human Rhinovirus (HRV14) infected, monocyte derived-DCs
Clone	#7-239
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.