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Mouse Monoclonal anti-Human CD16 Antibody


Item#:
xAP-0128
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0128
ID Mouse Monoclonal anti-Human CD16 Antibody
Antigen Description CD16 is known as low affinity IgG receptor III (Fc¿RIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc¿RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (Fc¿RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Size 100ug
Immunogen NK cell-enriched fraction from human peripheral blood.
Clone #B73.1
Antibody Isotype Mouse IgG1, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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