Mouse Monoclonal anti-Human CD16 Antibody

Item#:

xAP-0127

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0127
ID	Mouse Monoclonal anti-Human CD16 Antibody
Antigen Description	CD16 is known as low affinity IgG receptor III (Fc¿RIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc¿RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (Fc¿RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).
Size	100ug
Immunogen	Human PMN cells
Clone	#3G8
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC CyTOF®Block IHC-F IP Stim
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.