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Mouse Monoclonal anti-Human CD126 (IL-6Ra) Antibody

Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0082
ID Mouse Monoclonal anti-Human CD126 (IL-6Ra) Antibody
Antigen Description CD126 is an 80 kD IL-6 receptor a chain also known as IL-6R. It is a member of the immunoglobulin superfamily that is expressed on plasma cells, T cells, activated B cells, monocytes, granulocytes, hepatocytes, epithelial cells, and fibroblasts. Functional IL-6 receptors are formed by the non-covalent association of CD126 and the IL-6 receptor ß chain (CD130 or gp130). CD126 binds IL-6 with low affinity but does not signal. The ß chain (gp130, CD130) does not bind IL-6 by itself but associates with the a-chain/IL-6 complex to initiate signal transduction. IL-6 binding to the receptor complex results in the stimulation of B and T cells, and hematopoietic precursor proliferation and differentiation. A soluble form of CD126 has been found in human serum.
Size 100ug
Immunogen Human myeloma cell line U266
Clone #UV4
Antibody Isotype Mouse IgG1, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.