Mouse Monoclonal anti-Human CD116 Antibody

Item#:

xAP-0061

Size	Price	Quantity
100.0 ug	$320.00

Catalog Number	xAP-0061
ID	Mouse Monoclonal anti-Human CD116 Antibody
Antigen Description	CD116 is a 70-85 kD a chain of the GM-CSF receptor. It combines with CDw131 ß chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.
Size	100ug
Immunogen	Human GM-CSFRa transfected COS cells
Clone	#4H1
Antibody Isotype	Mouse IgG1, ¿
Species Reactivity	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC IP WB IHC-P IHC-F
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.