Mouse Monoclonal anti-Human CD105 Antibody

Item#:

xAP-0052

Size	Price	Quantity
100.0 ug	$400.00

Catalog Number	xAP-0052
ID	Mouse Monoclonal anti-Human CD105 Antibody
Antigen Description	CD105 is also known as Endoglin. It is a type I integral membrane homodimer protein with subunits of 90 kD found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on activated monocytes and tissue macrophages. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. CD105 is a component of the TGF-ß receptor system in human umbilical vein endothelial cells and binds TGF-ß1 and ß3 with high affinity but does not bind to TGF-ß2.
Size	100ug
Immunogen	L-cells transfected with human CD105
Clone	#43A3
Antibody Isotype	Mouse IgG1
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.