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Mouse Monoclonal anti-Human CD105 Antibody


Item#:
xAP-0052
Size Price Quantity
100.0 ug $320.00
Catalog Number xAP-0052
ID Mouse Monoclonal anti-Human CD105 Antibody
Antigen Description CD105 is also known as Endoglin. It is a type I integral membrane homodimer protein with subunits of 90 kD found on vascular endothelial cells and syncytiotrophoblasts of placenta. CD105 is weakly expressed on stromal fibroblasts. It is also expressed on activated monocytes and tissue macrophages. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation. CD105 is a component of the TGF-ß receptor system in human umbilical vein endothelial cells and binds TGF-ß1 and ß3 with high affinity but does not bind to TGF-ß2.
Size 100ug
Immunogen L-cells transfected with human CD105
Clone #43A3
Antibody Isotype Mouse IgG1, ¿
Species Reactivity Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application FC
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.

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