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Mouse Monoclonal anti-Copper ATPase 1 Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0023
ID Mouse Monoclonal anti-Copper ATPase 1 Antibody
Antigen Description Copper ATPase 1, also known as ATP7A, is a copper-transporting ATPase which uses ATP hydrolysis to transport copper ions across membranes to regulate intracellular copper levels. As copper is an important trace nutrient required for cellular health, ATP7A is widely expressed in most tissues. For example, ATP7A expression in enterocytes in the small intestine controls dietary uptake of copper from digested food. Disruptions to the ATP7A gene result in Menkes disease, whose symptoms are caused by copper deficiency. 
Size 100ug
Immunogen Synthetic peptide corresponding to amino acids 42-61 of recombinant human Copper ATPase 1
Clone #L60/4
Antibody Isotype Mouse IgG2b
Host Species Mouse
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application IHC-P
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.