Mouse Monoclonal anti-CD49e (Integrin a5) Antibody

Item#:

xAP-0019

Size	Price	Quantity
100.0 ug	$420.00

Catalog Number	xAP-0019
ID	Mouse Monoclonal anti-CD49e (Integrin a5) Antibody
Antigen Description	CD49e is a type I integral membrane glycoprotein, known as a5 integrin, or VLA-5 a chain. It forms noncovalent heterodimer with integrin ß1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronectin and neural adhesion molecule L1. It mediates monocytes migration, it is involved in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
Size	100ug
Immunogen	The P1D6 monoclonal antibody was generated against human HT1080 fibrosarcoma cells and reacts with the a5 integrin subunit.
Clone	#P1D6
Antibody Isotype	Mouse IgG3
Host Species	Mouse
Preparation	The antibody was purified by affinity chromatography.
Formulation	The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application	FC
Storage & Handling	Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.