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Rat Monoclonal anti-CCL11 (Eotaxin) Antibody

Size Price Quantity
100.0 ug $400.00
Catalog Number xAP-0015
ID Rat Monoclonal anti-CCL11 (Eotaxin) Antibody
Antigen Description CCL11 is a member of the CC chemokine family and was originally identified as a chemoattractant for eosinophils. In response to allergens, CCL11, which participates in a variety of allergic diseases, promotes accumulation of eosinophils. CCL11 production is upregulated in response to several proinflammatory cytokines, such as IL-4, IL-13, TNF-a, and IFN-a, produced by mast cells and Th2 lymphocytes. CCL11 has been reported to stimulate eosinophil release from bone marrow, resulting in an elevated level of circulating eosinophils. In addition, CCL11 facilitates proliferation and metastasis of tumor cells expressing the CCL11 receptor, CCR3. CCL11 has been shown to induce an angiogenic response by CCR3-positive microvascular endothelial cells.
Size 100ug
Immunogen Human CCL11 recombinant protein (Gly24-Pro97) expressed in E. coli
Clone #16D10A40
Antibody Isotype Rat IgG2a
Host Species Rat
Preparation The antibody was purified by affinity chromatography.
Formulation The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS).
Application WB
Storage & Handling Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 0.5mg/ml. Reconstituted antibody can also be aliquoted and stored frozen at < -20C for at least for six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.